Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ALA-LYS-PRO-GLU-ALA-PRO-GLY-GLU-ASP-ALA-SER-PRO-GLU-GLU-LEU-SER-ARG-TYR-TYR-ALA-SER-LEU-ARG-HIS-TYR-LEU-ASN-LEU-VAL-THR-ARG-GLN-ARG-TYR-NH2
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Purity: 98.0%
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Taiwan Oyi peptide Co. Ltd
China
Product Name: Peptide YY Fragment 3-36 human
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

126339-09-1

126339-09-1 structure

126339-09-1 structure

Name: Peptide YY Fragment 3-36 human
Chemical Name: Peptide YY (PYY) (3-36), human
CAS Number: 126339-09-1
Molecular Formula: C₁₇₆H₂₇₂N₅₂O₅₄
Molecular Weight: 3980.42
Catalog: Peptides
Create Date: 2018-03-09 06:30:14
Modify Date: 2024-01-05 18:18:36
Peptide YY (PYY) (3-36), human is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.

Name	Peptide YY (PYY) (3-36), human
Synonyms	MFCD00165623

Description	Peptide YY (PYY) (3-36), human is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Peptides
Target	Y2 receptor[1]
In Vitro	Peptide YY (PYY) (3-36), human is a Y2 receptor agonist, generated via cleaving the first two amino acids at the N terminus of PYY1-36 by enzyme dipeptidyl peptidase-IV (DPP-IV), and can reduces food intake[1].
In Vivo	In mice, actinonin significantly prolongs the anorectic effect of PYY3-36 (50 nmol/kg) and maintains higher PYY3-36 plasma levels than treatment with PYY3-36 alone[1].
Animal Admin	Mice[1] Mice are divided into four treatment groups and administered an injection (maximum volume, 100 μL, sc) of either: 1) saline (n = 10), 2) phosphoramidon (10 mg/kg) (n = 10), 3) PYY3-36 (50 nmol/kg) (n = 10), or 4) PYY3-36 (50 nmol/kg) and phosphoramidon (10 mg/kg) (n = 10). This dose of phosphoramidon inhibits NEP activity for 4 h. Body weight is measured at 0 and 24 h after injection. Food intake is measured at 1, 2, 3, 4, 8, and 24 h after injection[1].
References	[1]. Addison ML, et al. A role for metalloendopeptidases in the breakdown of the gut hormone, PYY 3-36. Endocrinology. 2011 Dec;152(12):4630-40.

Molecular Formula	C₁₇₆H₂₇₂N₅₂O₅₄
Molecular Weight	3980.42
Appearance	lyophilized powder
Storage condition	−20°C

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