439080-01-0

439080-01-0 structure
439080-01-0 structure
  • Name: O-2093
  • Chemical Name: (5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)-5,8,11,14-icosatetraenamide
  • CAS Number: 439080-01-0
  • Molecular Formula: C34H43Cl2NO3
  • Molecular Weight: 584.62
  • Create Date: 2018-07-19 23:37:13
  • Modify Date: 2024-01-14 12:31:31
  • O-2093 is a selective endocannabinoid anandamide (AEA) reuptake inhibitor with IC50 of 17.3 μM[1].

Name (5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)-5,8,11,14-icosatetraenamide
Synonyms 5,8,11,14-Eicosatetraenamide, N,N-bis[(3-chloro-4-hydroxyphenyl)methyl]-, (5Z,8Z,11Z,14Z)-
(5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)icosa-5,8,11,14-tetraenamide
(5Z,8Z,11Z,14Z)-N,N-Bis(3-chloro-4-hydroxybenzyl)-5,8,11,14-icosatetraenamide
Description O-2093 is a selective endocannabinoid anandamide (AEA) reuptake inhibitor with IC50 of 17.3 μM[1].
Related Catalog
In Vivo O-2093 (1 mg/kg, i.v.) 可显着抑制 CREATE 小鼠的肢体痉挛[1]。
References

[1]. Alessia Ligresti, et al. New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis.  

Density 1.1±0.1 g/cm3
Boiling Point 715.1±60.0 °C at 760 mmHg
Molecular Formula C34H43Cl2NO3
Molecular Weight 584.62
Flash Point 386.3±32.9 °C
Exact Mass 583.262024
LogP 9.69
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.579