170847-18-4
170847-18-4 structure
- Name: (RS)-APICA
- Chemical Name: 1-Amino-5-phosphono-1-indanecarboxylic acid
- CAS Number: 170847-18-4
- Molecular Formula: C10H12NO5P
- Molecular Weight: 257.18
- Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
- Create Date: 2018-07-21 14:01:44
- Modify Date: 2025-08-26 18:54:55
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APICA is a potent CB1 and CB2 receptors agonist with EC50 values of 118 nM and 37 nM against CB1 and CB2 receptors, respectively. APICA possess cannabimimetic activity in vivo[1].
| Name | 1-Amino-5-phosphono-1-indanecarboxylic acid |
|---|---|
| Synonyms |
1-Amino-5-phosphono-1-indanecarboxylic acid
1H-Indene-1-carboxylic acid, 1-amino-2,3-dihydro-5-phosphono- 1-Amino-5-phosphonoindane-1-carboxylic acid |
| Description | APICA is a potent CB1 and CB2 receptors agonist with EC50 values of 118 nM and 37 nM against CB1 and CB2 receptors, respectively. APICA possess cannabimimetic activity in vivo[1]. |
|---|---|
| Related Catalog | |
| Target |
hCB2-R:37 nM (EC50) hCB1-R:118 nM (EC50) |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 559.9±60.0 °C at 760 mmHg |
| Molecular Formula | C10H12NO5P |
| Molecular Weight | 257.18 |
| Flash Point | 292.4±32.9 °C |
| Exact Mass | 257.045319 |
| LogP | -0.89 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.671 |