(RS)-APICA

Modify Date: 2025-08-26 18:54:55

(RS)-APICA Structure
(RS)-APICA structure
Common Name (RS)-APICA
CAS Number 170847-18-4 Molecular Weight 257.18
Density 1.6±0.1 g/cm3 Boiling Point 559.9±60.0 °C at 760 mmHg
Molecular Formula C10H12NO5P Melting Point N/A
MSDS N/A Flash Point 292.4±32.9 °C

 Use of (RS)-APICA


APICA is a potent CB1 and CB2 receptors agonist with EC50 values of 118 nM and 37 nM against CB1 and CB2 receptors, respectively. APICA possess cannabimimetic activity in vivo[1].

 Names

Name 1-Amino-5-phosphono-1-indanecarboxylic acid
Synonym More Synonyms

 (RS)-APICA Biological Activity

Description APICA is a potent CB1 and CB2 receptors agonist with EC50 values of 118 nM and 37 nM against CB1 and CB2 receptors, respectively. APICA possess cannabimimetic activity in vivo[1].
Related Catalog
Target

hCB2-R:37 nM (EC50)

hCB1-R:118 nM (EC50)

References

[1]. Longworth M, et al. Synthesis and Pharmacological Profiling of the Metabolites of Synthetic Cannabinoid Drugs APICA, STS-135, ADB-PINACA, and 5F-ADB-PINACA. ACS Chem Neurosci. 2017 Aug 16;8(8):1673-1680.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 559.9±60.0 °C at 760 mmHg
Molecular Formula C10H12NO5P
Molecular Weight 257.18
Flash Point 292.4±32.9 °C
Exact Mass 257.045319
LogP -0.89
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.671

 Synonyms

1-Amino-5-phosphono-1-indanecarboxylic acid
1H-Indene-1-carboxylic acid, 1-amino-2,3-dihydro-5-phosphono-
1-Amino-5-phosphonoindane-1-carboxylic acid
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