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1134188-26-3

1134188-26-3 structure
1134188-26-3 structure
  • Name: Epimagnolin B
  • Chemical Name: (1R,3aR,4S,6aR)-1-(3,5-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
  • CAS Number: 1134188-26-3
  • Molecular Formula: C23H28O7
  • Molecular Weight: 416.464
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-07-05 00:40:16
  • Modify Date: 2024-01-06 19:40:56
  • Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].

Name (1R,3aR,4S,6aR)-1-(3,5-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
Synonyms (1R,3aR,4S,6aR)-1-(3,5-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
1H,3H-Furo[3,4-c]furan, 1-(3,5-dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-, (1R,3aR,4S,6aR)-
Description Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].
Related Catalog
In Vitro Epimagnolin B exhibits antiallergic effects without affecting the viability of BMMCs[1].
References

[1]. Kim JY, et al. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40.

[2]. Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects.  RSC Advances. July 2017;7(54):34236-34243.

Density 1.2±0.1 g/cm3
Boiling Point 548.2±50.0 °C at 760 mmHg
Molecular Formula C23H28O7
Molecular Weight 416.464
Flash Point 220.9±30.0 °C
Exact Mass 416.183502
LogP 2.75
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.542
Storage condition 2-8℃