Epimagnolin B

Modify Date: 2024-01-06 19:40:56

Epimagnolin B Structure
Epimagnolin B structure
Common Name Epimagnolin B
CAS Number 1134188-26-3 Molecular Weight 416.464
Density 1.2±0.1 g/cm3 Boiling Point 548.2±50.0 °C at 760 mmHg
Molecular Formula C23H28O7 Melting Point N/A
MSDS N/A Flash Point 220.9±30.0 °C

 Use of Epimagnolin B


Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].

 Names

Name (1R,3aR,4S,6aR)-1-(3,5-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
Synonym More Synonyms

 Epimagnolin B Biological Activity

Description Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].
Related Catalog
In Vitro Epimagnolin B exhibits antiallergic effects without affecting the viability of BMMCs[1].
References

[1]. Kim JY, et al. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40.

[2]. Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects.  RSC Advances. July 2017;7(54):34236-34243.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 548.2±50.0 °C at 760 mmHg
Molecular Formula C23H28O7
Molecular Weight 416.464
Flash Point 220.9±30.0 °C
Exact Mass 416.183502
LogP 2.75
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.542
Storage condition 2-8℃

 Synonyms

(1R,3aR,4S,6aR)-1-(3,5-Dimethoxyphenyl)-4-(3,4,5-trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
1H,3H-Furo[3,4-c]furan, 1-(3,5-dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-, (1R,3aR,4S,6aR)-
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