202982-98-7

202982-98-7 structure

Name: NF 340
Chemical Name: Tetrasodium 4,4'-{carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]}di(2,6-naphthalenedisulfonate)
CAS Number: 202982-98-7
Molecular Formula: C₃₇H₂₆N₄Na₄O₁₅S₄
Molecular Weight: 986.84
Catalog: Signaling Pathways GPCR/G Protein P2Y Receptor
Create Date: 2018-07-20 21:58:39
Modify Date: 2024-01-12 05:02:18
NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].

Name	Tetrasodium 4,4'-{carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]}di(2,6-naphthalenedisulfonate)
Synonyms	2,6-Naphthalenedisulfonic acid, 4,4'-[carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]]bis-, sodium salt (1:4) Tetrasodium 4,4'-{carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]}di(2,6-naphthalenedisulfonate)

Description	NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> P2Y Receptor Research Areas >> Inflammation/Immunology
Target	P2Y11 receptor[1]
References	[1]. Feng Gao, et al. P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis. IUBMB Life. 2019 Oct;71(10):1552-1560.