NF 340

Modify Date: 2024-01-12 05:02:18

NF 340 Structure
NF 340 structure
Common Name NF 340
CAS Number 202982-98-7 Molecular Weight 986.84
Density N/A Boiling Point N/A
Molecular Formula C37H26N4Na4O15S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NF 340


NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].

 Names

Name Tetrasodium 4,4'-{carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]}di(2,6-naphthalenedisulfonate)
Synonym More Synonyms

 NF 340 Biological Activity

Description NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].
Related Catalog
Target

P2Y11 receptor[1]

References

[1]. Feng Gao, et al. P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis. IUBMB Life. 2019 Oct;71(10):1552-1560.

 Chemical & Physical Properties

Molecular Formula C37H26N4Na4O15S4
Molecular Weight 986.84
Exact Mass 985.986816

 Synonyms

2,6-Naphthalenedisulfonic acid, 4,4'-[carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]]bis-, sodium salt (1:4)
Tetrasodium 4,4'-{carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]}di(2,6-naphthalenedisulfonate)
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