660846-99-1

660846-99-1 structure

Name: Ac-Arg-Gly-Lys-AMC trifluoroacetate salt
Chemical Name: N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide
CAS Number: 660846-99-1
Molecular Formula: C₂₆H₃₈N₈O₆
Molecular Weight: 558.63
Catalog: Research Areas Others
Create Date: 2018-07-02 11:25:07
Modify Date: 2024-01-09 22:23:28
Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

Name	N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide
Synonyms	L-Lysinamide, N2-acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- N2-Acetyl-L-arginylglycyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide Ac-Arg-Gly-Lys-AMC trifluoroacetate salt

Description	Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Noonepalle S, et, al. Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models. J Med Chem. 2020 Sep 24;63(18):10246-10262.