236403-25-1

236403-25-1 structure

Name: MMP-8 INHIBITOR I
Chemical Name: (3R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
CAS Number: 236403-25-1
Molecular Formula: C₁₇H₁₈N₂O₅S
Molecular Weight: 362.40
Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
Create Date: 2018-06-29 08:03:37
Modify Date: 2025-09-01 19:06:37
MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1].

Name	(3R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
Synonyms	(3R)-N-Hydroxy-2-[(4-methoxyphenyl)sulfonyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide 3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-

Description	MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP-8
References	[1]. Matter H, et al. Tetrahydroisoquinoline-3-carboxylate based matrix-metalloproteinase inhibitors: design, synthesis and structure-activity relationship. Bioorg Med Chem. 2002 Nov;10(11):3529-44.