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  • BioBioPha
  • China
  • Product Name: Kushenol M
  • Price: ¥4250.0/5mg
  • Purity: 96.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng


101236-51-5

101236-51-5 structure
101236-51-5 structure
  • Name: Kushenol M
  • Chemical Name: (2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
  • CAS Number: 101236-51-5
  • Molecular Formula: C30H36O7
  • Molecular Weight: 508.603
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
  • Create Date: 2018-07-01 14:32:38
  • Modify Date: 2024-01-11 00:00:51
  • Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC50 values of 1.29 μM for CYP3A4 in in human liver microsomes[1].

Name (2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
Synonyms 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-6-(3-methyl-2-buten-1-yl)-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2R,3R)-
(2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
Description Kushenol M is a flavonoid from Sophora flavescens. Kushenol M is a cytochrome P450 (CYP) inhibitor, with IC50 values of 1.29 μM for CYP3A4 in in human liver microsomes[1].
Related Catalog
References

[1]. Xinguang Liu, et al. Advances in Metabolic Profiling and Pharmacokinetics of Herbal Medicinal Products. Evid Based Complement Alternat Med. 2019 May 6;2019:5190972.

Density 1.2±0.1 g/cm3
Boiling Point 737.7±60.0 °C at 760 mmHg
Molecular Formula C30H36O7
Molecular Weight 508.603
Flash Point 240.1±26.4 °C
Exact Mass 508.246094
LogP 7.84
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.619
Hazard Codes Xi