110988-86-8

110988-86-8 structure
110988-86-8 structure
  • Name: 2',2'-difluorodeoxycytidine 5'-triphosphate
  • Chemical Name: A0Q7SO4OZE
  • CAS Number: 110988-86-8
  • Molecular Formula: C9H14F2N3O13P3
  • Molecular Weight: 503.138
  • Catalog: Research Areas Cancer
  • Create Date: 2018-07-05 02:18:51
  • Modify Date: 2024-01-05 11:13:21
  • Gemcitabine triphosphate (dFdCTP) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells[1][2].

Name A0Q7SO4OZE
Synonyms A0Q7SO4OZE
gemcitabine triphosphate
Cytidine, 2'-deoxy-2',2'-difluoro-, 5'-(tetrahydrogen triphosphate)
2'-Deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate)
Description Gemcitabine triphosphate (dFdCTP) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells[1][2].
Related Catalog
References

[1]. Shewach DS, et al. Gemcitabine and radiosensitization in human tumor cells. Invest New Drugs. 1996;14(3):257-63.  

Density 2.4±0.1 g/cm3
Boiling Point 797.7±70.0 °C at 760 mmHg
Molecular Formula C9H14F2N3O13P3
Molecular Weight 503.138
Flash Point 436.2±35.7 °C
Exact Mass 502.970764
LogP -4.54
Vapour Pressure 0.0±6.4 mmHg at 25°C
Index of Refraction 1.724