148579-93-5
148579-93-5 structure
- Name: Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2
- Chemical Name: 4-Formyl-2-nitrophenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
- CAS Number: 148579-93-5
- Molecular Formula: C20H21NO13
- Molecular Weight: 483.380
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-06-12 19:04:41
- Modify Date: 2024-01-11 03:45:27
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Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Name | 4-Formyl-2-nitrophenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate |
|---|---|
| Synonyms |
4-Formyl-2-nitrophenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
Benzaldehyde, 3-nitro-4-[(2,3,4-tri-O-acetyl-6-methyl-β-D-glucopyranuronosyl)oxy]- |
| Description | Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Benatuil, Lorenzo, et al. Anti-B7-H3 antibodies and antibody drug conjugates. WO2017214339. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 582.6±50.0 °C at 760 mmHg |
| Molecular Formula | C20H21NO13 |
| Molecular Weight | 483.380 |
| Flash Point | 219.6±32.1 °C |
| Exact Mass | 483.101288 |
| LogP | 2.62 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.550 |