Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2

Modify Date: 2024-01-11 03:45:27

Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 Structure
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 structure
Common Name Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2
CAS Number 148579-93-5 Molecular Weight 483.380
Density 1.4±0.1 g/cm3 Boiling Point 582.6±50.0 °C at 760 mmHg
Molecular Formula C20H21NO13 Melting Point N/A
MSDS N/A Flash Point 219.6±32.1 °C

 Use of Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2


Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

 Names

Name 4-Formyl-2-nitrophenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
Synonym More Synonyms

  Biological Activity

Description Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Benatuil, Lorenzo, et al. Anti-B7-H3 antibodies and antibody drug conjugates. WO2017214339.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 582.6±50.0 °C at 760 mmHg
Molecular Formula C20H21NO13
Molecular Weight 483.380
Flash Point 219.6±32.1 °C
Exact Mass 483.101288
LogP 2.62
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.550

 Synonyms

4-Formyl-2-nitrophenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate
Benzaldehyde, 3-nitro-4-[(2,3,4-tri-O-acetyl-6-methyl-β-D-glucopyranuronosyl)oxy]-
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