400716-78-1

400716-78-1 structure

Name: Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 trifluoroacetate salt
Chemical Name: N-Acetyl-L-α-glutamyl-N-{2-[(5-sulfo-1-naphthyl)amino]ethyl}-L-asparaginyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucylglycyl-N6-(4-{(E)-[4-(dimethylamino)phenyl]diazenyl}benzoyl)-L-lysyl-L-α-glutamine
CAS Number: 400716-78-1
Molecular Formula: C₁₀₄H₁₄₆N₂₄O₂₃S
Molecular Weight: 2132.484
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cathepsin
Create Date: 2018-06-25 14:14:14
Modify Date: 2024-02-28 15:09:56
Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a cathepsin D substrate, that can be used for cathepsin D FRET assay[1].

Name	N-Acetyl-L-α-glutamyl-N-{2-[(5-sulfo-1-naphthyl)amino]ethyl}-L-asparaginyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucylglycyl-N6-(4-{(E)-[4-(dimethylamino)phenyl]diazenyl}benzoyl)-L-lysyl-L-α-glutamine
Synonyms	L-α-Glutamine, N-acetyl-L-α-glutamyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-asparaginyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucylglycyl-N6- [4-[(E)-2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysyl- N-Acetyl-L-α-glutamyl-N-{2-[(5-sulfo-1-naphthyl)amino]ethyl}-L-asparaginyl-L-lysyl-L-prolyl-L-isoleucyl-L-leucyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-leucylglycyl-N6-(4-{(E)-[4-(dimethylami no)phenyl]diazenyl}benzoyl)-L-lysyl-L-α-glutamine

Description	Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a cathepsin D substrate, that can be used for cathepsin D FRET assay[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Target	Cathepsin D
References	[1]. Eketjäll S, et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. J Alzheimers Dis. 2016;50(4):1109-23.