416901-58-1

416901-58-1 structure

Name: COX-2-IN-5
Chemical Name: LM-1685
CAS Number: 416901-58-1
Molecular Formula: C₁₈H₁₆ClNO₄S
Molecular Weight: 377.842
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2018-07-11 01:12:38
Modify Date: 2024-01-07 11:27:44
COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 µM. COX-2-IN-5 has the potential for the research of inflammation[1].

Name	LM-1685
Synonyms	LM-1685 Methyl 1-(4-chlorobenzyl)-5-(methylsulfonyl)-1H-indole-2-carboxylate 1H-Indole-2-carboxylic acid, 1-[(4-chlorophenyl)methyl]-5-(methylsulfonyl)-, methyl ester

Description	COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 µM. COX-2-IN-5 has the potential for the research of inflammation[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2:0.65 μM (IC50)
References	[1]. Palomer A, et al. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. J Med Chem. 2002 Mar 28;45(7):1402-11.