416901-58-1
416901-58-1 structure
- Name: COX-2-IN-5
- Chemical Name: LM-1685
- CAS Number: 416901-58-1
- Molecular Formula: C18H16ClNO4S
- Molecular Weight: 377.842
- Catalog: Signaling Pathways Immunology/Inflammation COX
- Create Date: 2018-07-11 01:12:38
- Modify Date: 2024-01-07 11:27:44
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COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 µM. COX-2-IN-5 has the potential for the research of inflammation[1].
| Name | LM-1685 |
|---|---|
| Synonyms |
LM-1685
Methyl 1-(4-chlorobenzyl)-5-(methylsulfonyl)-1H-indole-2-carboxylate 1H-Indole-2-carboxylic acid, 1-[(4-chlorophenyl)methyl]-5-(methylsulfonyl)-, methyl ester |
| Description | COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 µM. COX-2-IN-5 has the potential for the research of inflammation[1]. |
|---|---|
| Related Catalog | |
| Target |
COX-2:0.65 μM (IC50) |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 604.3±55.0 °C at 760 mmHg |
| Molecular Formula | C18H16ClNO4S |
| Molecular Weight | 377.842 |
| Flash Point | 319.3±31.5 °C |
| Exact Mass | 377.048859 |
| LogP | 2.73 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.620 |