COX-2-IN-5

Modify Date: 2024-01-07 11:27:44

COX-2-IN-5 Structure
COX-2-IN-5 structure
Common Name COX-2-IN-5
CAS Number 416901-58-1 Molecular Weight 377.842
Density 1.4±0.1 g/cm3 Boiling Point 604.3±55.0 °C at 760 mmHg
Molecular Formula C18H16ClNO4S Melting Point N/A
MSDS N/A Flash Point 319.3±31.5 °C

 Use of COX-2-IN-5


COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 µM. COX-2-IN-5 has the potential for the research of inflammation[1].

 Names

Name LM-1685
Synonym More Synonyms

 COX-2-IN-5 Biological Activity

Description COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 µM. COX-2-IN-5 has the potential for the research of inflammation[1].
Related Catalog
Target

COX-2:0.65 μM (IC50)

References

[1]. Palomer A, et al. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. J Med Chem. 2002 Mar 28;45(7):1402-11.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 604.3±55.0 °C at 760 mmHg
Molecular Formula C18H16ClNO4S
Molecular Weight 377.842
Flash Point 319.3±31.5 °C
Exact Mass 377.048859
LogP 2.73
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.620

 Synonyms

LM-1685
Methyl 1-(4-chlorobenzyl)-5-(methylsulfonyl)-1H-indole-2-carboxylate
1H-Indole-2-carboxylic acid, 1-[(4-chlorophenyl)methyl]-5-(methylsulfonyl)-, methyl ester