51012-67-0

51012-67-0 structure

Name: Verapamil EP Impurity C hydrochloride
Chemical Name: 2-(3,4-Dimethoxyphenyl)-N,N-dimethylethanamine hydrochloride (1:1)
CAS Number: 51012-67-0
Molecular Formula: C₁₂H₂₀ClNO₂
Molecular Weight: 245.746
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2018-07-02 15:51:12
Modify Date: 2024-01-06 20:32:56
NSC-609249 hydrochloride is an impurity of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor[1][2].

Name	2-(3,4-Dimethoxyphenyl)-N,N-dimethylethanamine hydrochloride (1:1)
Synonyms	2-(3,4-Dimethoxyphenyl)-N,N-dimethylethanamine hydrochloride (1:1) Benzeneethanamine, 3,4-dimethoxy-N,N-dimethyl-, hydrochloride (1:1)

Description	NSC-609249 hydrochloride is an impurity of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein Research Areas >> Metabolic Disease
References	[1]. Gowarty JL, et al. Verapamil as a culprit of palbociclib toxicity. J Oncol Pharm Pract. 2019 Apr;25(3):743-746. [2]. Krikler DM. Verapamil in arrhythmia. Br J Clin Pharmacol. 1986;21 Suppl 2:183S-189S.