1443331-82-5

1443331-82-5 structure

Name: Enzalutamide D3
Chemical Name: 4-{3-[3-Cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl}-2-fluoro-N-(2H3)methylbenzamide
CAS Number: 1443331-82-5
Molecular Formula: C₂₁H₁₃D₃F₄N₄O₂S
Molecular Weight: 467.454
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2018-07-12 02:55:41
Modify Date: 2024-01-09 18:05:40
Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].

Name	4-{3-[3-Cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl}-2-fluoro-N-(2H3)methylbenzamide
Synonyms	4-{3-[3-Cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl}-2-fluoro-N-(2H3)methylbenzamide Benzamide, 4-[3-[3-cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-(methyl-d3)-

Description	Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Tran C, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009 May 8;324(5928):787-90.