Enzalutamide D3

Modify Date: 2024-01-09 18:05:40

Enzalutamide D3 Structure
Enzalutamide D3 structure
Common Name Enzalutamide D3
CAS Number 1443331-82-5 Molecular Weight 467.454
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C21H13D3F4N4O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Enzalutamide D3


Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].

 Names

Name 4-{3-[3-Cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl}-2-fluoro-N-(2H3)methylbenzamide
Synonym More Synonyms

 Enzalutamide D3 Biological Activity

Description Enzalutamide D3 is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells[1].
Related Catalog
References

[1]. Tran C, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009 May 8;324(5928):787-90.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C21H13D3F4N4O2S
Molecular Weight 467.454
Exact Mass 467.111847
LogP 2.13
Index of Refraction 1.630

 Synonyms

4-{3-[3-Cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl}-2-fluoro-N-(2H3)methylbenzamide
Benzamide, 4-[3-[3-cyano-4-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-(methyl-d3)-
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