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1404111-56-3

1404111-56-3 structure
1404111-56-3 structure
  • Name: Ald-Ph-amido-PEG3-C2-NH2
  • Chemical Name: Ald--Ph-PEG3-amine
  • CAS Number: 1404111-56-3
  • Molecular Formula: C16H24N2O5
  • Molecular Weight: 324.372
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-13 18:48:52
  • Modify Date: 2024-01-04 09:15:09
  • Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Ald--Ph-PEG3-amine
Synonyms ALD-PH-NH-PEG3-NH2
Description Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.2±0.1 g/cm3
Boiling Point 542.8±50.0 °C at 760 mmHg
Molecular Formula C16H24N2O5
Molecular Weight 324.372
Flash Point 282.1±30.1 °C
Exact Mass 324.168518
LogP -0.57
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.540
Hazard Codes Xi