1420043-61-3
1420043-61-3 structure
- Name: TolfenaMic acid-13C6
- Chemical Name: TolfenaMic acid-13C6
- CAS Number: 1420043-61-3
- Molecular Formula: C813C6H12ClNO2
- Molecular Weight: 267.659
- Catalog: analytical chemistry Standard Forensic and veterinary standards
- Create Date: 2018-12-17 11:01:09
- Modify Date: 2024-01-11 10:13:46
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Tolfenamic acid-13C6 is the 13C6 labeled Tolfenamic acid. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1.
| Name | TolfenaMic acid-13C6 |
|---|---|
| Synonyms |
2-[(3-Chloro-2-methylphenyl)amino](13C6)benzoic acid
MFCD23136996 2-(3-Chloro-2-methylphenylamino)benzoic-13C6 acid Benzoic-1,2,3,4,5,6-13C6 acid, 2-[(3-chloro-2-methylphenyl)amino]- Tolfenamic acid-(benzoic ring-13C6) |
| Description | Tolfenamic acid-13C6 is the 13C6 labeled Tolfenamic acid. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C813C6H12ClNO2 |
| Molecular Weight | 267.659 |
| Exact Mass | 267.075775 |
| Index of Refraction | 1.658 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| RIDADR | UN 2811 6.1 / PGIII |