Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Territrem B
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Territrem B
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: territrem B
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

70407-20-4

70407-20-4 structure

70407-20-4 structure

Name: Territrem B
Chemical Name: territrem B
CAS Number: 70407-20-4
Molecular Formula: C₂₉H₃₄O₉
Molecular Weight: 526.579
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-12-26 17:54:48
Modify Date: 2024-04-06 11:06:07
Territrem B is an irreversible inhibitor of Acetylcholinesterase (AChE) inhibitor. Territrem B is also a fungal meroterpenoid that can be isolated from Aspergillus terreus[1][2].

Name	territrem B
Synonyms	MFCD00869655

Description	Territrem B is an irreversible inhibitor of Acetylcholinesterase (AChE) inhibitor. Territrem B is also a fungal meroterpenoid that can be isolated from Aspergillus terreus[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	AChE
In Vitro	Territrem B 与 AChE 活性位点的结合常数 (Ki) 为 1.7 nM[2]。
References	[1]. Chen JW, et al. Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism. J Biol Chem. 1999 Dec 3;274(49):34916-23. [2]. Cheung J, et al. Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination. J Mol Neurosci. 2014 Jul;53(3):506-10.

Molecular Formula	C₂₉H₃₄O₉
Molecular Weight	526.579
Storage condition	2-8°C

Hazard Codes	T+