Territrem B

Modify Date: 2024-04-06 11:06:07

Territrem B Structure
Territrem B structure
Common Name Territrem B
CAS Number 70407-20-4 Molecular Weight 526.579
Density N/A Boiling Point N/A
Molecular Formula C29H34O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Territrem B


Territrem B is an irreversible inhibitor of Acetylcholinesterase (AChE) inhibitor. Territrem B is also a fungal meroterpenoid that can be isolated from Aspergillus terreus[1][2].

 Names

Name territrem B
Synonym More Synonyms

 Territrem B Biological Activity

Description Territrem B is an irreversible inhibitor of Acetylcholinesterase (AChE) inhibitor. Territrem B is also a fungal meroterpenoid that can be isolated from Aspergillus terreus[1][2].
Related Catalog
Target

AChE

In Vitro Territrem B 与 AChE 活性位点的结合常数 (Ki) 为 1.7 nM[2]。
References

[1]. Chen JW, et al. Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism. J Biol Chem. 1999 Dec 3;274(49):34916-23.  

[2]. Cheung J, et al. Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination. J Mol Neurosci. 2014 Jul;53(3):506-10.  

 Chemical & Physical Properties

Molecular Formula C29H34O9
Molecular Weight 526.579
Storage condition 2-8°C

 Safety Information

Hazard Codes T+

 Synonyms

MFCD00869655
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