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1258063-56-7

1258063-56-7 structure
1258063-56-7 structure
  • Name: Cortodoxone-d5
  • Chemical Name: 11-Deoxycortisol-[D5]
  • CAS Number: 1258063-56-7
  • Molecular Formula: C21H25D5O4
  • Molecular Weight: 351.491
  • Create Date: 2018-07-10 01:58:49
  • Modify Date: 2024-01-09 16:09:30
  • Cortodoxone-d5 (11-Deoxycortisol-d5) is the deuterium labeled Cortodoxone.

Name 11-Deoxycortisol-[D5]
Synonyms Cortexolone-2,2,4,6,6-d5
11-DEOXYCORTISOL-2,2,4,6,6-D5
17,21-Dihydroxy(2,2,4,6,6-2H5)pregn-4-ene-3,20-dione
Reichstein's substance S (2,2,4,6,6-d5)
Cortodoxone-D5 (2,2,4,6,6-D5)
EINECS 200-659-6
11-Deoxy-17-hydroxycorticosterone-2,2,4,6,6-d5
Pregn-4-ene-3,20-dione-2,2,4,6,6-d5, 17,21-dihydroxy-
17,21-Dihydroxyprogesterone-2,2,4,6,6-d5
11-Deoxycortisol-D5 (2,2,4,6,6-D5) solution
11-Desoxycortisol-D5 (2,2,4,6,6-D5)
11-Deoxycortisol-D5 (2,2,4,6,6-D5)
MFCD15144809
Description Cortodoxone-d5 (11-Deoxycortisol-d5) is the deuterium labeled Cortodoxone.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Density 1.2±0.1 g/cm3
Boiling Point 524.5±50.0 °C at 760 mmHg
Melting Point 208 °C (dec.)
Molecular Formula C21H25D5O4
Molecular Weight 351.491
Flash Point 285.1±26.6 °C
Exact Mass 351.245789
LogP 2.74
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.578
Storage condition 20°C
RIDADR NONH for all modes of transport