DC Chemicals Limited
China
Product Name: Tos-PEG5-CH2CO2tBu
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tos-PEG5-CH2CO2t-butyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

169751-73-9

169751-73-9 structure

169751-73-9 structure

Name: Tos-PEG4-CH2-Boc
Chemical Name: Tos-PEG5-CH2CO2t-butyl ester
CAS Number: 169751-73-9
Molecular Formula: C₂₁H₃₄O₉S
Molecular Weight: 462.554
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-19 01:50:27
Modify Date: 2024-01-09 20:24:26
Tos-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Tos-PEG5-CH2CO2t-butyl ester
Synonyms	2-Methyl-2-propanyl 14-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12-tetraoxatetradecan-1-oate 3,6,9,12-Tetraoxatetradecan-1-oic acid, 14-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester MFCD27977499

Description	Tos-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Density	1.2±0.1 g/cm3
Boiling Point	550.0±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₃₄O₉S
Molecular Weight	462.554
Flash Point	286.4±30.1 °C
Exact Mass	462.192352
LogP	1.86
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.493

Hazard Codes	Xi