1802908-02-6
1802908-02-6 structure
- Name: Methyltetrazine-PEG4-maleimide
- Chemical Name: Tetrazine-PEG4-maleimide
- CAS Number: 1802908-02-6
- Molecular Formula: C24H30N6O7
- Molecular Weight: 613.662
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-20 15:03:40
- Modify Date: 2024-01-05 10:01:48
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Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Tetrazine-PEG4-maleimide |
|---|---|
| Synonyms |
Methyltetrazine-PEG4-maleimide
1H-Pyrrole-1-butanamide, 2,5-dihydro-N-[17-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]-15-oxo-3,6,9,12-tetraoxa-16-azaheptadec-1-yl]-2,5-dioxo- 20-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl]-17-oxo-4,7,10,13-tetraoxa-16-azaicosan-1-amide MFCD28053555 Tetrazine-PEG4-maleimide |
| Description | Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C24H30N6O7 |
| Molecular Weight | 613.662 |
| Exact Mass | 613.286011 |
| LogP | -2.38 |
| Index of Refraction | 1.556 |
| Storage condition | -20°C |