Methyltetrazine-PEG4-maleimide

Modify Date: 2025-09-13 06:56:48

Methyltetrazine-PEG4-maleimide Structure
Methyltetrazine-PEG4-maleimide structure
Common Name Methyltetrazine-PEG4-maleimide
CAS Number 1802908-02-6 Molecular Weight 613.662
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C24H30N6O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methyltetrazine-PEG4-maleimide


Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tetrazine-PEG4-maleimide
Synonym More Synonyms

 Methyltetrazine-PEG4-maleimide Biological Activity

Description Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C24H30N6O7
Molecular Weight 613.662
Exact Mass 613.286011
LogP -2.38
Index of Refraction 1.556
InChIKey DPEUPJJPNNSKGW-UHFFFAOYSA-N
SMILES Cc1nnc(-c2ccc(OCCOCCOCCOCCNC(=O)CCN3C(=O)C=CC3=O)cc2)nn1
Storage condition -20°C

 Safety Information

Hazard Codes Xi
Risk Phrases 36/38
Safety Phrases 26

 Synonyms

Methyltetrazine-PEG4-maleimide
1H-Pyrrole-1-butanamide, 2,5-dihydro-N-[17-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]-15-oxo-3,6,9,12-tetraoxa-16-azaheptadec-1-yl]-2,5-dioxo-
20-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzyl]-17-oxo-4,7,10,13-tetraoxa-16-azaicosan-1-amide
MFCD28053555
Tetrazine-PEG4-maleimide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Methyltetrazine-PEG4-maleimide suppliers

Methyltetrazine-PEG4-maleimide price

Related Compounds: More...
tert-Butyl (2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethyl)carbamate
2194563-84-1
Methyltetrazine-PEG4-azide
1802908-04-8
1-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenoxy)-3,6,9,12-tetraoxapentadecan-15-oic acid
1802907-91-0
Methyltetrazine-PEG4-amine HCl
1802908-05-9
DBCO-PEG4-Maleimide
1480516-75-3
Alkyne-PEG4-maleimide
1609651-90-2
PC Methyltetrazine-PEG4-NHS carbonate ester
2055736-28-0
Sulfo DBCO-PEG4-Maleimide
2055198-07-5
Methyltetrazine-amido-N-bis(PEG4-acid)
2639395-39-2
N-cycloheptyl-2-[(2-methoxyphenyl)amino]-5-oxo-5H-[1,3,4]thiadiazolo[2,3-b]quinazoline-8-carboxamide
894251-67-3
2-(3-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-3-oxopropyl)-6,7,8,9-tetrahydro-3H-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4(5H)-one
950443-92-2
N-(1-benzylpiperidin-4-yl)-3-(7-(tert-butyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)propanamide
950444-12-9
N-(3,5-dichlorophenyl)-2-[(1-methyl-5-phenyl-1H-imidazol-2-yl)sulfanyl]acetamide
946256-23-1
2-((5-(4-chlorophenyl)-1-methyl-1H-imidazol-2-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
921816-74-2
Ethyl 1-(2-methylphenyl)-4-{[(4-methylphenyl)methyl]amino}-6-oxo-1,6-dihydropyridazine-3-carboxylate
922015-14-3
Ethyl 4-{[(2-methoxyphenyl)methyl]amino}-1-(2-methylphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylate
921989-26-6
6-{[4-(2-oxo-2H-chromene-3-carbonyl)piperazin-1-yl]sulfonyl}-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4(12),5,7-trien-11-one
946361-17-7
2-[2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethan-1-amine
951547-49-2
4-methoxy-N-{2-[2-(thiophen-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}benzene-1-sulfonamide
946273-77-4