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760952-64-5

760952-64-5 structure
760952-64-5 structure
  • Name: Mal-PEG1-acid
  • Chemical Name: Mal-PEG1-acid
  • CAS Number: 760952-64-5
  • Molecular Formula: C9H11NO5
  • Molecular Weight: 213.187
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-06-13 00:05:12
  • Modify Date: 2024-01-17 12:25:18
  • Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

Name Mal-PEG1-acid
Synonyms 3-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]propanoic acid
MFCD24497443
Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-
Description Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Karpov AS, et al. Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody-Drug Conjugates. ACS Med Chem Lett. 2018 Jun 28;9(8):838-842.

Density 1.4±0.1 g/cm3
Boiling Point 419.4±30.0 °C at 760 mmHg
Molecular Formula C9H11NO5
Molecular Weight 213.187
Flash Point 207.5±24.6 °C
Exact Mass 213.063721
LogP -0.37
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.541
Hazard Codes Xi