Top Suppliers:I want be here


99217-64-8

99217-64-8 structure
99217-64-8 structure
  • Name: Kushenol B
  • Chemical Name: Kushenol B
  • CAS Number: 99217-64-8
  • Molecular Formula: C30H36O6
  • Molecular Weight: 492.603
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
  • Create Date: 2019-01-10 17:33:41
  • Modify Date: 2024-01-21 12:03:22
  • Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 µM[1].

Name Kushenol B
Synonyms 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-6-(3-methyl-2-buten-1-yl)-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2S)-
(2S)-2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-6-(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
Description Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities[1]. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 µM[1].
Related Catalog
Target

IC50: 31 µM (cAMP PDE)[1]

References

[1]. Han-Tian Fan, et al. The rational search for PDE10A inhibitors from Sophora flavescens roots using pharmacophore‑ and docking‑based virtual screening. Mol Med Rep

Density 1.2±0.1 g/cm3
Boiling Point 702.3±60.0 °C at 760 mmHg
Molecular Formula C30H36O6
Molecular Weight 492.603
Flash Point 228.2±26.4 °C
Exact Mass 492.251190
LogP 8.61
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.605
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.