79902-42-4

79902-42-4 structure

Name: 2'-Ethyl Simvastatin
Chemical Name: <1S-<1α,3α,7β,8β(2S*,4S*)8aβ>>-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-<2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl>-1-naphthalenyl 2-methylpropionate
CAS Number: 79902-42-4
Molecular Formula: C₂₃H₃₄O₅
Molecular Weight: 390.51300
Catalog: Signaling Pathways Metabolic Enzyme/Protease HMG-CoA Reductase (HMGCR)
Create Date: 2018-07-07 13:39:00
Modify Date: 2024-01-10 10:42:36
2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, with HMG-CoA reductase inhibition[1].

Name	<1S-<1α,3α,7β,8β(2S,4S)8aβ>>-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-<2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl>-1-naphthalenyl 2-methylpropionate
Synonyms	[1S-(1α,3α,7β,8β(2S,4S)8aβ)]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2-methylpropionate zocor Isobutyric acid (1S,3R,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester

Description	2'-Ethyl Simvastatin (compound 6) is a Mevinolin analog, with HMG-CoA reductase inhibition[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)
Target	HMG-CoA reductase[1]
References	[1]. AGGARWAL, D., et al. A quantitative structure-activity relationship study of 3-hydroxy-3methylglutaryl-coenzyme A reductase inhibitors. Journal of Pharmacobio-Dynamics, 1988;11(9), 591–599.