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2166487-21-2

2166487-21-2 structure
2166487-21-2 structure
  • Name: SIRT5 inhibitor
  • Chemical Name: SIRT5 inhibitor
  • CAS Number: 2166487-21-2
  • Molecular Formula: C31H39FN6O6S2
  • Molecular Weight: 674.81
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Sirtuin
  • Create Date: 2019-01-20 12:06:00
  • Modify Date: 2024-01-08 19:08:44
  • SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.

Name SIRT5 inhibitor
Description SIRT5 inhibitor is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.
Related Catalog
Target

IC50: 0.11 μM (Sirtuin)[1].

In Vitro SIRT5 inhibitor (compound 49) is a very potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM, >100-fold from compound 1[1].
References

[1]. Rajabi N, et al. Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14836-14841.

Molecular Formula C31H39FN6O6S2
Molecular Weight 674.81