2115701-93-2
2115701-93-2 structure
- Name: (+)-JQ1 PA
- Chemical Name: (+)-JQ1 PA
- CAS Number: 2115701-93-2
- Molecular Formula: C22H20ClN5OS
- Molecular Weight: 437.95
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2019-01-20 01:33:34
- Modify Date: 2024-01-10 05:50:56
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(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC50 of 10.4 nM.
| Name | (+)-JQ1 PA |
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| Description | (+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1, with an IC50 of 10.4 nM. |
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| Related Catalog | |
| Target |
10.4 nM (BET)[1]. |
| In Vitro | (+)-JQ1 PA is a derivative of JQ1, which is the inhibitor of BET. The IC50 of (+)-JQ1 PA for BET is 10.4 nM, and the IC50 of JQ1 is 14.3 nM in MV4;11 cells[1]. |
| Cell Assay | Proliferation of MV4;11 cells after 72 hours of treatment, comparing JQ1 versus JQ1-PA are tested. Cell cycle profile of MV4;11 cells after 48 hours of treatment with DMSO, JQ1, JQ1-PA, or JQ1-TCO (all compounds used at 500 nM) are tested[1]. |
| References |
| Molecular Formula | C22H20ClN5OS |
|---|---|
| Molecular Weight | 437.95 |