Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Desoxycarbadox-D3
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Purity: 97.0%
Stocking Period: 10 Day
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1448350-02-4

1448350-02-4 structure

1448350-02-4 structure

Name: Desoxycarbadox-D3
Chemical Name: Desoxycarbadox-D3
CAS Number: 1448350-02-4
Molecular Formula: C₁₁H₇D₃N₄O₂
Molecular Weight: 233.241
Catalog: analytical chemistry Standard Forensic and veterinary standards
Create Date: 2019-01-20 00:02:01
Modify Date: 2024-01-08 00:11:46
Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.

Name	Desoxycarbadox-D3
Synonyms	Hydrazinecarboxylic acid, 2-(2-quinoxalinylmethylene)-, methyl-d3 ester, (2E)- (2H3)Methyl (2E)-2-(2-quinoxalinylmethylene)hydrazinecarboxylate

Description	Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [2]. MacIntosh AI, et al. Liquid chromatographic monitoring of the depletion of carbadox and its metabolite desoxycarbadox in swine tissues. J Assoc Off Anal Chem. 1985;68(4):665-671. [3]. Looft T, et al. Carbadox has both temporary and lasting effects on the swine gut microbiota. Front Microbiol. 2014;5:276. Published 2014 Jun 10. [4]. Zhang K, et al. Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites. Environ Toxicol Pharmacol. 2015;39(2):555-567.

Density	1.3±0.1 g/cm3
Molecular Formula	C₁₁H₇D₃N₄O₂
Molecular Weight	233.241
Exact Mass	233.099213
LogP	1.72
Index of Refraction	1.634

Symbol	GHS02, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H228-H302-H350
Precautionary Statements	P201-P210-P308 + P313
Hazard Codes	F,T
Risk Phrases	R45-11-22
Safety Phrases	S53-45
RIDADR	UN1325 - class 4.1 - PG 2 - Flammable solids, organic, n.o.s., HI: all