1213827-99-6
1213827-99-6 structure
- Name: AN-3485
- Chemical Name: AN-3485
- CAS Number: 1213827-99-6
- Molecular Formula: C14H13BClNO3
- Molecular Weight: 289.52
- Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
- Create Date: 2019-02-25 11:31:36
- Modify Date: 2024-01-02 09:26:13
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AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM.
| Name | AN-3485 |
|---|
| Description | AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. |
|---|---|
| Related Catalog | |
| Target |
IC50：AN-3485 inhibits TLR2-, TLR3-, TLR4-, and TLR5-mediates TNF-a, IL-1b, and IL-6 release with IC50 values of human PBMCs (103±68 nM, 68±63 nM, 72±33 nM)and isolated monocytes (77±26 nM; 18±6.7 nM; 32±6.5 nM) [1] . |
| References |
| Molecular Formula | C14H13BClNO3 |
|---|---|
| Molecular Weight | 289.52 |