Name | AN-3485 |
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Description | AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. |
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Related Catalog | |
Target |
IC50:AN-3485 inhibits TLR2-, TLR3-, TLR4-, and TLR5-mediates TNF-a, IL-1b, and IL-6 release with IC50 values of human PBMCs (103±68 nM, 68±63 nM, 72±33 nM)and isolated monocytes (77±26 nM; 18±6.7 nM; 32±6.5 nM) [1] . |
References |
Molecular Formula | C14H13BClNO3 |
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Molecular Weight | 289.52 |