1452473-54-9
1452473-54-9 structure
- Name: GOAT-IN-1
- Chemical Name: GOAT-IN-1
- CAS Number: 1452473-54-9
- Molecular Formula: C18H13ClF3NO3S
- Molecular Weight: 415.81
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Acyltransferase
- Create Date: 2019-02-09 02:21:42
- Modify Date: 2025-08-21 18:31:29
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GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.
| Name | GOAT-IN-1 |
|---|---|
| Synonyms |
Benzo[b]thiophene-3-acetic acid, 4-chloro-6-[[2-methyl-6-(trifluoromethyl)-3-pyridinyl]methoxy]
GOATIN1,GOAT IN 1 (4-Chloro-6-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methoxy)-1-benzothiophen-3-yl)acetic acid |
| Description | GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors. |
|---|---|
| Related Catalog | |
| In Vitro | The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM[1]. |
| References |
[1]. WO 2013125732. |
| Molecular Formula | C18H13ClF3NO3S |
|---|---|
| Molecular Weight | 415.81 |