Top Suppliers:I want be here


1114546-03-0

1114546-03-0 structure
1114546-03-0 structure
  • Name: Androgen receptor modulators 1
  • Chemical Name: Androgen receptor modulators 1
  • CAS Number: 1114546-03-0
  • Molecular Formula: C14H13F3N2O2
  • Molecular Weight: 298.26
  • Catalog: Research Areas Cancer
  • Create Date: 2019-03-03 10:57:17
  • Modify Date: 2024-01-07 06:02:15
  • Androgen receptor modulators 1 is a selective androgen receptor modulator (SARM). Androgen receptor modulators 1 has strong agonistic activities with an EC50 of 4.7 nM[1].

Name Androgen receptor modulators 1
Description Androgen receptor modulators 1 is a selective androgen receptor modulator (SARM). Androgen receptor modulators 1 has strong agonistic activities with an EC50 of 4.7 nM[1].
Related Catalog
Target

EC50: 4.7 nM (SARM)[1]

In Vitro Androgen receptor modulators 1 (Compounds 2f) induces sexual behavior at the minimal dose (0.5 mg/kg/day, qd, po). It could act as androgen agonist on the CNS[1]. Androgen receptor modulators 1 shows good metabolic stabilities with little species difference between rat, dog, mouse, monkey and human[1].
References

[1]. Aikawa K, et al. Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate. Bioorg Med Chem. 2017 Jul 1;25(13):3330-3349.

Molecular Formula C14H13F3N2O2
Molecular Weight 298.26
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.