1401728-56-0
1401728-56-0 structure
- Name: GPR4 antagonist 3
- Chemical Name: GPR4 antagonist 3
- CAS Number: 1401728-56-0
- Molecular Formula: C24H28N6O
- Molecular Weight: 416.52
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2019-03-03 10:22:07
- Modify Date: 2024-01-14 15:13:26
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GPR4 antagonist 3 is a selective, and orally available GPR4 antagonist with an IC50 of 70 nM[1]. Anti-inflammatory activities[1].
| Name | GPR4 antagonist 3 |
|---|
| Description | GPR4 antagonist 3 is a selective, and orally available GPR4 antagonist with an IC50 of 70 nM[1]. Anti-inflammatory activities[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 70 nM (GPR4)[1]. |
| In Vivo | GPR4 antagonist 3 shows a significant anti-inflammatory effect in the rat antigen induced arthritis model after oral administration at 30 mg/kg bid[1].GPR4 antagonist 3 also prevents angiogenesis in the mouse chamber model as well as pain as demonstrated in the rat complete Freund’s adjuvant model[1]. |
| References |
| Molecular Formula | C24H28N6O |
|---|---|
| Molecular Weight | 416.52 |