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Product Name: AZ-3
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2228908-91-4

2228908-91-4 structure

2228908-91-4 structure

Name: AZ-3
Chemical Name: AZ-3
CAS Number: 2228908-91-4
Molecular Formula: C₂₀H₂₈FN₇
Molecular Weight: 385.48
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2019-03-31 10:32:34
Modify Date: 2025-08-26 14:54:31
AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM.

Name	AZ-3

Description	AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	IC50: 34 nM (JAK1)[1]
References	[1]. Grimster NP, et al. Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors. J Med Chem. 2018 Jun 28;61(12):5235-5244.

Molecular Formula	C₂₀H₂₈FN₇
Molecular Weight	385.48

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