1801530-11-9

1801530-11-9 structure

Name: Imidazole ketone erastin(IKE)
Chemical Name: Imidazole ketone erastin
CAS Number: 1801530-11-9
Molecular Formula: C₃₅H₃₅ClN₆O₅
Molecular Weight: 655.14
Catalog: Signaling Pathways Apoptosis Ferroptosis
Create Date: 2019-03-31 08:56:34
Modify Date: 2025-08-25 08:45:10
Imidazole ketone erastin (IKE) s a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system Xc- and an activator of ferroptosis.

Name	Imidazole ketone erastin

Description	Imidazole ketone erastin (IKE) s a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system Xc- and an activator of ferroptosis.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
Target	System Xc-, ferroptosis[1]
References	[1]. Zhang Y, et al. Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model. Cell Chem Biol. 2019 Jan 31. pii: S2451-9456(19)30030-3.