Imidazole ketone erastin(IKE)

Modify Date: 2024-01-05 07:43:06

Imidazole ketone erastin(IKE) Structure
Imidazole ketone erastin(IKE) structure
Common Name Imidazole ketone erastin(IKE)
CAS Number 1801530-11-9 Molecular Weight 655.14
Density N/A Boiling Point N/A
Molecular Formula C35H35ClN6O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Imidazole ketone erastin(IKE)


Imidazole ketone erastin (IKE) s a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system Xc- and an activator of ferroptosis.

 Names

Name Imidazole ketone erastin

 Imidazole ketone erastin(IKE) Biological Activity

Description Imidazole ketone erastin (IKE) s a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system Xc- and an activator of ferroptosis.
Related Catalog
Target

System Xc-, ferroptosis[1]

References

[1]. Zhang Y, et al. Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model. Cell Chem Biol. 2019 Jan 31. pii: S2451-9456(19)30030-3.

 Chemical & Physical Properties

Molecular Formula C35H35ClN6O5
Molecular Weight 655.14
Storage condition 2-8℃