Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ODM-204
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Purity: 98.0%
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1642818-64-1

1642818-64-1 structure

1642818-64-1 structure

Name: ODM-204
Chemical Name: ODM-204
CAS Number: 1642818-64-1
Molecular Formula: C₂₀H₂₁F₃N₄
Molecular Weight: 374.40
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2019-03-30 11:31:34
Modify Date: 2025-08-25 10:54:53
ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme, with IC50s of 80 nM and 22 nM, respectively.

Name	ODM-204

Description	ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme, with IC50s of 80 nM and 22 nM, respectively.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Signaling Pathways >> Others >> Androgen Receptor
Target	IC50: 80 nM (Androgen receptor), 22 nM (CYP17A1 enzyme)[1]
References	[1]. Oksala R, et al. Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1. J Steroid Biochem Mol Biol. 2018 Feb 10. pii: S0960-0760(18)30078-5.

Molecular Formula	C₂₀H₂₁F₃N₄
Molecular Weight	374.40

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