Top Suppliers:I want be here
Related CAS#:
1262751-08-5 138831-86-4
1262750-80-0 141312-45-0
199533-16-9 98849-88-8
2022956-62-1 2990-43-4
1315378-77-8 51543-40-9

1262751-08-5

1262751-08-5 structure
1262751-08-5 structure
  • Name: OVA Peptide (257-264) TFA
  • Chemical Name: OVA Peptide (257-264) TFA
  • CAS Number: 1262751-08-5
  • Molecular Formula: C47H75F3N10O15
  • Molecular Weight: 1077.15
  • Catalog: Research Areas Others
  • Create Date: 2019-03-30 18:21:34
  • Modify Date: 2024-01-03 13:11:11
  • OVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Name OVA Peptide (257-264) TFA
Description OVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Related Catalog
In Vitro TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide (257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide (257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide (257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide (257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1].
Cell Assay TAPl-/- or C57BL/6 macrophages are co-incubated with either bacteria or polystyrene beads containing the 257-264 epitope from ovalbumin [OVA Peptide (257-264)], which binds the mouse class I molecule Kb. The source of the OVA(257-264) epitope is either the Crl-OVA(257-264) (Crl-OVA) fusion protein, the maltose binding protein (MBP)-Crl-OVA fusion protein, native OVA or bacterial recombinant OVA (rOVA); Crl-OVA, MBP-Crl-OVA and rOVA are each expressed in bacteria, and Crl-OVA and MBP-Crl-OVA purified from bacterial lysates and native egg OVA are coated onto polystyrene beads[1].
References

[1]. Wick MJ, et al. Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: protein context influences the degree of TAP-independent presentation. Eur J Immunol. 1996 Nov;26(11):2790-9.
Molecular Formula C47H75F3N10O15
Molecular Weight 1077.15

Chemsrc provides CAS#:1262751-08-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1262751-08-5 | Chemsrc address: https://m.chemsrc.com/en/baike/1557400.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved