Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-chloro-2-N-[2-methoxy-4-[4-[(4-methylpiperazin-1-yl)methyl]triazol-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: WY-135
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: WY-135
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

2163060-83-9

2163060-83-9 structure

2163060-83-9 structure

Name: WY-135
Chemical Name: WY-135
CAS Number: 2163060-83-9
Molecular Formula: C₂₈H₃₄ClN₉O₃S
Molecular Weight: 612.15
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2019-03-31 10:02:34
Modify Date: 2024-04-13 18:12:28
WY-135 is a ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.

Name	WY-135

Description	WY-135 is a ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
Target	IC50: 1.4 nM (ALK), 1.1 nM (ROS1)[1]
References	[1]. Wang Y, et al. Discovery of novel 2,4-diarylaminopyrimidine analogues as ALK and ROS1 dual inhibitors to overcome crizotinib-resistant mutants including G1202R. Eur J Med Chem. 2018 Jan 1;143:123-136.

Molecular Formula	C₂₈H₃₄ClN₉O₃S
Molecular Weight	612.15