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  • DC Chemicals Limited
  • China
  • Product Name: Acy-1083
  • Price: ¥Inquiry/100mg ¥Inquiry/250mg ¥Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Tony Cao

1708113-43-2

1708113-43-2 structure
1708113-43-2 structure
  • Name: ACY-1083
  • Chemical Name: ACY-1083
  • CAS Number: 1708113-43-2
  • Molecular Formula: C17H18F2N4O2
  • Molecular Weight: 348.35
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
  • Create Date: 2019-06-01 20:49:50
  • Modify Date: 2024-01-09 18:11:02
  • ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC50 of 3 nM and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms. ACY-1083 effectively reverses chemotherapy-induced peripheral neuropathy[1].

Name ACY-1083
Description ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor with an IC50 of 3 nM and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms. ACY-1083 effectively reverses chemotherapy-induced peripheral neuropathy[1].
Related Catalog
Target

HDAC6:3 nM (IC50)

References

[1]. Krukowski K, et al. HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy. Pain. 2017 Jun;158(6):1126-1137.

Molecular Formula C17H18F2N4O2
Molecular Weight 348.35
Storage condition 2-8℃