Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

328565-16-8

328565-16-8 structure

328565-16-8 structure

Name: Col 003
Chemical Name: Col003
CAS Number: 328565-16-8
Molecular Formula: C₁₄H₁₁NO₄
Molecular Weight: 257.24
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2019-06-01 14:34:56
Modify Date: 2026-07-16 10:40:51
Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].

Name	Col003
Synonyms	Col003, 10 mM in DMSO Benzaldehyde, 2-hydroxy-3-nitro-5-(phenylmethyl) Col003 >= (HPLC) MEF,structure,Hsp47,triple,helix,collagen,Col003,Col-003,secretion,HSP,Heat shock proteins,Inhibitor,Col 003,inhibit,interaction

Description	Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	HSP47:1.8 μM (IC50)
References	[1]. Ito S, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017 Dec 8;292(49):20076-20085.

Molecular Formula	C₁₄H₁₁NO₄
Molecular Weight	257.24

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.