DC Chemicals Limited
China
Product Name: Col 003
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

328565-16-8

328565-16-8 structure

328565-16-8 structure

Name: Col 003
Chemical Name: Col003
CAS Number: 328565-16-8
Molecular Formula: C₁₄H₁₁NO₄
Molecular Weight: 257.24
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2019-06-01 14:34:56
Modify Date: 2024-01-09 18:31:51
Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].

Name	Col003

Description	Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	HSP47:1.8 μM (IC50)
References	[1]. Ito S, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017 Dec 8;292(49):20076-20085.

Molecular Formula	C₁₄H₁₁NO₄
Molecular Weight	257.24