Col 003

Modify Date: 2024-01-09 18:31:51

Col 003 structure	Common Name	Col 003
	CAS Number	328565-16-8	Molecular Weight	257.24
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₁NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Col 003

Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].

Name	Col003

Description	Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	HSP47:1.8 μM (IC50)
References	[1]. Ito S, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017 Dec 8;292(49):20076-20085.

Molecular Formula	C₁₄H₁₁NO₄
Molecular Weight	257.24

DC Chemicals Limited
China
Product Name: Col 003
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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