1373409-08-5

1373409-08-5 structure

Name: EML4-ALK kinase inhibitor 1
Chemical Name: EML4-ALK kinase inhibitor 1
CAS Number: 1373409-08-5
Molecular Formula: C₃₁H₄₈N₈O₃
Molecular Weight: 580.76
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ALK
Create Date: 2019-06-01 18:10:00
Modify Date: 2024-01-02 21:42:44
EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM[1].

Name	EML4-ALK kinase inhibitor 1

Description	EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ALK
Target	IC50: 1 nM (EML4-ALK)[1].
References	[1]. Iikubo K, et al. Synthesis and structure-activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1683-1692.

Molecular Formula	C₃₁H₄₈N₈O₃
Molecular Weight	580.76