EML4-ALK kinase inhibitor 1

Modify Date: 2025-09-11 13:28:39

EML4-ALK kinase inhibitor 1 Structure
EML4-ALK kinase inhibitor 1 structure
 Common Name EML4-ALK kinase inhibitor 1
CAS Number 1373409-08-5 Molecular Weight 580.76
Density N/A Boiling Point N/A
Molecular Formula C31H48N8O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EML4-ALK kinase inhibitor 1


EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM[1].

 Names

Name EML4-​ALK kinase inhibitor 1

 EML4-ALK kinase inhibitor 1 Biological Activity

Description EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM[1].
Related Catalog
Target

IC50: 1 nM (EML4-ALK)[1].

References

[1]. Iikubo K, et al. Synthesis and structure-activity relationships of pyrazine-2-carboxamide derivatives as novel echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1683-1692.

 Chemical & Physical Properties

Molecular Formula C31H48N8O3
Molecular Weight 580.76
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