187325-53-7

187325-53-7 structure

Name: GSK-3β inhibitor 1
Chemical Name: GSK-3β inhibitor 1
CAS Number: 187325-53-7
Molecular Formula: C₁₄H₁₀N₂O
Molecular Weight: 222.24
Catalog: Signaling Pathways PI3K/Akt/mTOR GSK-3
Create Date: 2019-06-01 11:31:50
Modify Date: 2025-08-20 16:29:23
GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].

Name	GSK-3β inhibitor 1

Description	GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Metabolic Disease Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3
Target	GSK-3β:4.9 nM (IC50)
References	[1]. Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.